IgA nephropathy in Blacks: Studies of IgA2 allotypes and clinical course

Clinical course and prognostic factors of clinical early IgA nephropathy.

BACKGROUND Immunoglobulin A nephropathy (IgAN) is prevalent in many countries including China. At the time of diagnosis many IgAN patients present with normal renal function, proteinuria of 0.4 g/d or less, and normal blood pressure and they are classified as clinically early IgAN patients. However, the natural history of clinically early IgAN and prognostic factors has not yet been clarified. ...

Clinical, Histopathological and Immunofluorescent Findings of IgA Nephropathy

Background: IgA nephropathy, a prevalent disease in Asia, is considered the main cause of end stage renal disease among primary glomerular disease. Objective: To determine the frequency of different clinical, histopathological and immunofluorescent characteristics of IgA nephropathy. Methods: Renal biopsies of 376 patients were received for immunofluorescent and for histopathological studies. B...

Comment on: Clinical, Histopathological and Immunofluorescent Findings of IgA Nephropathy

Genetic studies of IgA nephropathy.

IgA nephropathy is the commonest form of glomerulonephritis worldwide, but we still know relatively little about its pathogenesis. Potentially, genetic studies might provide new insights and suggest novel therapeutic approaches to this important cause of chronic kidney disease. Two approaches that are likely to yield new information are analysis of multiply affected pedigrees and large-scale, w...

IgA Nephropathy and Significance of Immunostaining Data